Rozebalamin for Intramuscular Injection 25mg
Mecobalamin injection for ALS | Japanese medicine information
Rozebalamin (ロゼバラミン)
A high-dose mecobalamin preparation manufactured by Eisai in Japan. This information supports consultation preparation; a doctor must assess suitability.
Approved use in Japan
Rozebalamin is approved in Japan to slow the progression of functional impairment in ALS. It is not a cure for ALS. Numbness or fatigue alone is not a reason to use this medicine. A doctor experienced in ALS should assess suitability using the disease course and clinical findings.
How does it differ from Methycobal tablets?
Rozebalamin injection
- 25mg per vial, administered by intramuscular injection.
- Approved in Japan for slowing functional impairment progression in ALS.
- Preparation and administration must follow the prescription and medical guidance.
Methycobal tablets
- 500μg = 0.5mg per tablet, taken orally.
- Approved in Japan for peripheral neuropathy.
- View Methycobal tablet information
These products contain the same active ingredient but have different formulations, strengths and approved uses. They are not interchangeable; taking more tablets does not replace injection treatment.
Administration, storage and precautions
Administration and storage
- Follow the prescription and complete package insert for the dose, schedule and preparation method. 25mg is the labelled strength per vial.
- Store at room temperature. Protect from light after opening, and follow the package insert’s light-protection instructions during preparation and administration.
- The photograph illustrates the packaging and does not confirm current availability, batch or expiry date.
Tell your doctor before treatment
- Do not use if you have a history of allergy to any ingredient in this medicine.
- The label lists serious allergic reactions, including anaphylactic shock. Seek urgent medical care for breathing difficulties or other severe symptoms.
- Discuss your medical history, allergies, current medicines, and pregnancy or breastfeeding status.
Prepare for your consultation
Prepare your ALS diagnosis records, symptom-onset and diagnosis dates, current treatment plan and prescription details. Suitability, prescribing and availability must be confirmed with the doctor and service provider.
Official sources
Eisai product information and package insert (Japanese) · PMDA patient medicine guide (Japanese)
Source information checked on 7 October 2026. This page provides medicine information and consultation preparation; it does not replace diagnosis, a prescription or medical advice.